Prenatal acetaminophen exposure in meconium and the risk of ADHD- Role of Confounding by Indication
Motherisk Int J 2020;1;24 Gideon Koren MD FRCPC FACMT Professor and Head of Pharmacology, Adelson School of Medicine, Ariel University, Israel E mail: gidiup_2000@yahoo.com Tel 972587194777 Jacob V. Aranda MD, PhD, FRCPC, FAAP Professor of Pediatrics and Ophthalmology and Director of Neonatology State University of New York Downstate Health Sciences University Question: In…
Read MoreSalivary Melatonin Levels in Pregnant Women with Insomnia: A Prospective Controlled Study
Motherisk Int J 2020;1;23 Kamelia Mirdamadi1,2, Gideon Koren,3,4 University of Toronto, Department of Pharmaceutical Sciences, Toronto, ON, Ca Hospital for Sick Children, Division of Clinical Pharmacology and Toxicology, Toronto, ON Ariel University, Department of Clinical Pharmacology, Israel Motherisk Israel Program Corresponding Author: Kamelia Mirdamadi Leslie Dan Faculty of Pharmacy, Department of Pharmaceutical Sciences 144…
Read MoreWomen using antiepileptic drugs: How much folic acid per day is sufficient?
Motherisk Int J 2020;1;22 Yusuf Cem Kaplan MD (1), Gideon Koren MD (2, 3) Independent Researcher, Berlin, Germany (1), Adelson Faculty of Medicine, Ariel University (2) and Motherisk Israel Program (3) Question: I have a patient who has been receiving lamotrigine for her focal onset seizures. She is considering pregnancy and asked me…
Read MoreCovid-19 re-infection in pregnancy?
Motherisk Int J 2020;1;21 Gideon Koren MD FRCPC FACMT, Vered Nachmias Friedler MD MBA, Renato Fusman MD, Susy Mann RN Leumit Health Services and Adelson School of Medicine, Ariel University, Israel Question This week I have seen several media reports of Covid-19 proven- re infections. Because pregnancy appears to be a risk factor…
Read MoreEfficacy of a daily prenatal supplement of folic acid; how many cases of spina bifida can be prevented?
motherisk int j 2020;1:20 Yonah Amitai MD, The Meuchedet Insurance Fund and Bar Ilan University, Israel. Question: I am confused: The FDA claims that folic acid prevents 50-70% of neural tube defects. But population-based American studies show only a 20-30% prevention rate. Where is the catch here? Answer: In the US there…
Read MoreBonjesta- the first dual release combination of doxylamine-pyridoxine for morning sickness
Motherisk Intl J 2020;1;19 Bonjesta- the first dual release combination of doxylamine-pyridoxine for morning sickness Gideon Koren, Rana Cohen, Adelson School of Medicine, Ariel University and Motherisk Israel Program Question: The delayed release of doxylamine/ pyridoxine (Diclegis®) works well in many of my patients with morning sickness. The problem I have is that it…
Read MoreFetal alcohol spectrum disorder in twin pregnancies
Motherisk Int J 2020;1:18 Gideon Koren MD, FRCPC, FACMT and Rana Cohen BSc Pharm, MBA Adelson School of Medicine, Ariel University and Motherisk Israel Program Question: If a heavily drinking mother has twins, are both affected by FASD? Answer: Not necessarily. Studies in humans and experiments in laboratory animals reveal full concordance in…
Read MoreMotherisk Rounds: Neural Tube Defects and Dydrogesterone
Motherisk Int J 2020;1:17 Gideon Koren MD FRCPC FACMT Ariel University and Motherisk Israel, Shamir Medical Center Question: We have a case of cervical insufficiency resulting in two miscarriages of otherwise normal fetuses. In the subsequent two pregnancies the woman received dydrogesterone (DYD). In both cases the fetuses were diagnosed with encephalocele and…
Read MoreThe Risks of Codeine to Breastfed Infants- Facts and Fallacies
Motherisk Int J 2020;1:16 David Chitayat MD, FRCPC, FACCG (1) and Gideon Koren MD, FRCPC, FACMT (2) The Prenatal Diagnosis and Medical Genetics Program, Department of Obstetrics and Gynecology, Mount Sinai Hospital, The University of Toronto, ON, Canada (1); Motherisk International Program and Ariel University, Ariel, Israel (2) Question: It has been…
Read MoreMotherisk International Guide for the Diagnosis and Differential Diagnosis of Fetal Alcohol Spectrum Disorder (FASD)
Motherisk Int J 2020;1:15 Gideon Koren MD FRCPC FACMT Question: I am looking for a source of information that not only tells me the basics of diagnosing fetal alcohol spectrum disorder (FASD), but also the differential diagnosis I need to consider. Answer: To address this important question, we present here the fourth edition…
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