Medication -induced neural tube defects- a scoping review
Motherisk Int J 2020;1;25 Gideon Koren MD FRCPC FACMT(1,2), Asher Ornoy MD(1,3) Adelson School of Medicine, Ariel University (1) Motherisk International program (2), Hebrew University Hadassah Medical School, Jerusalem Israel 40700 gidiup_2000@yahoo.com Tel 9272587194777 Abstract Over the last 40 years a large body of research has examined potential correlations between neural tube…
Read MoreWomen using antiepileptic drugs: How much folic acid per day is sufficient?
Motherisk Int J 2020;1;22 Yusuf Cem Kaplan MD (1), Gideon Koren MD (2, 3) Independent Researcher, Berlin, Germany (1), Adelson Faculty of Medicine, Ariel University (2) and Motherisk Israel Program (3) Question: I have a patient who has been receiving lamotrigine for her focal onset seizures. She is considering pregnancy and asked me…
Read MoreEfficacy of a daily prenatal supplement of folic acid; how many cases of spina bifida can be prevented?
motherisk int j 2020;1:20 Yonah Amitai MD, The Meuchedet Insurance Fund and Bar Ilan University, Israel. Question: I am confused: The FDA claims that folic acid prevents 50-70% of neural tube defects. But population-based American studies show only a 20-30% prevention rate. Where is the catch here? Answer: In the US there…
Read MoreMotherisk Rounds: Neural Tube Defects and Dydrogesterone
Motherisk Int J 2020;1:17 Gideon Koren MD FRCPC FACMT Ariel University and Motherisk Israel, Shamir Medical Center Question: We have a case of cervical insufficiency resulting in two miscarriages of otherwise normal fetuses. In the subsequent two pregnancies the woman received dydrogesterone (DYD). In both cases the fetuses were diagnosed with encephalocele and…
Read MoreHigh-Dose Gestational Folic Acid and the Risk for Autism? The Birth Order Effect
Motherisk Int J 2020;1:1 Gideon Koren MD, Motherisk Israel Program and Ariel University; Address for Correspondence: Gideon Koren MD FRCPC FACMT Clinical Pharmacology Program, Shamir Hospital, and Adelson Faculty of Medicine, Ariel Univeristy, Isral Tel 972 587194777 gidiup_2000@yahoo.com Abstract: Question: Recent publications suggested that high dose folic acid is associated with increased risk…
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